inflammation and changes in SOCS gene expression Effect of ovariectomy on cardiac gene expression

Summary of mRNA showing twofold or greater change between ovariectomized and estrogen-replaced rats Replaced (OVX/E2) Rats’Ratio of Expression inOVX/E2:OVX1 or 2 in OVXCompared WithEST Treated mRNA GenBank Inflammation Related0.361 1 suppressor of cytokine signaling 2 (SOCS2) AF0753820.107 1 suppressor of cytokine signaling 3 (SOCS3) AF075383 0.273 1 CD59 protein precursor U48255 0.015 1 complement C8 beta (C8b), partial cds U20194 0.364 1 glutathione S-transferase Yc1 subunit (GST Yc1); GST-alpha K019320.253 1 glutathione S-transferase M3 (GSTM3); GST YB3 J02744 0.303 1 calpain II 80 kDa subunit L09120 0.156 1 calpain; CLS4 D144790.395 1 calpain Lp82 U963670.230 1 kallistatin U510170.242 1 killer cell lectin-like receptor subfamily D member 1 (KLRD1); CD94 antigen AF009133 0.036 1 calpain small subunit 1 (CSS1) U53859 0.351 1 natural killer cell receptor P1B (NKR-P1B) X97477 0.164 1 lymphotoxin (TNF-beta) gene, tumor necrosis factor (TNF-alpha) L00981 0.327 1 geranylgeranyl transferase component A L137220.230 1 NAD-dependent 15-hydroxyprostaglandin dehydrogenase (HPGD) U447500.218 1 skeletal muscle selenoprotein W (SELW; SEPW) U25264