Mesenchymal Stem Cell Extracellular Vesicles as Adjuvant to Bone Marrow Stimulation in Chondral Defect Repair in a Minipig Model

Kris Chadwick Hede,Bjørn Borsøe Christensen,Morten Lykke Olesen,Jesper Skovhus Thomsen,Casper Bindzus Foldager,Wei Seong Toh,Sai Kiang Lim,Martin Lind

Mesenchymal Stem Cell Extracellular Vesicles as Adjuvant to Bone Marrow Stimulation in Chondral Defect Repair in a Minipig Model

2021

Kris Chadwick Hede
Bjørn Borsøe Christensen
Morten Lykke Olesen
Jesper Skovhus Thomsen
Casper Bindzus Foldager
Wei Seong Toh
Sai Kiang Lim
Martin Lind

ObjectiveThis study evaluated the effects of mesenchymal stem cell-extracellular vesicles (MSC-EVs) on chondrocyte proliferation in vitro and on cartilage repair in vivo following bone marrow stimu...

Keywords:

Chondrocyte
In vivo
Adjuvant
In vitro
Cell biology
Stimulation
Vesicle
Bone marrow
Mesenchymal stem cell
Chemistry

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