Aminostyrylbenzofuran derivatives as inhibitors against beta-amyloid fibril formation, and pharmaceutical composition comprising same

PURPOSE: An aminostyrylbenzofuran compound and a pharmaceutical composition containing the same are provided to prevent and treat neurodegenerative diseases caused by beta-amyloid fibrillation. CONSTITUTION: A compound is selected among an aminostyrylbenzofuran compound of chemical formula 1 and a pharmaceutically acceptable salt, an isomer, a hydrate, and a solvate thereof. A pharmaceutical composition which suppresses beta-fibrillation contains the compound as an active ingredient. A pharmaceutical composition for preventing or treating neurodegenerative diseases contains the compound as an active ingredient. The neurodegenerative diseases are senile dementia, stroke, Parkinson's disease, Huntington's disease, or bovine spongiform encephalopathy.