3-(5,7-Di­methoxy-2,2-di­methyl-2H-benzo­[b]­pyran-6-yl)­propionic acid: a potential inhibitor against Leishmania

The title acid, C16H20O5, was extracted from Adiscanthus fusciflorus (Rutaceae) and is shown to inhibit adenine phospho­ribosyl­transferase (APRT) enzyme activity. This compound crystallizes in the centrosymmetric space group C2/c with one mol­ecule in the asymmetric unit. There is one strong hydrogen bond, with OD⋯OA = 2.6238 (12) A and OD—H⋯OA = 171.1 (17)° involving the COOH group, forming a cyclic dimer about a center of symmetry. The packing of the mol­ecules is additionally stabilized by one C—H⋯O [CD⋯OA = 2.9820 (16) A and CD—H⋯OA = 101.8 (10)°] and two C—H⋯π intermolecular hydrogen bonds.