Clinical diagnosis and integrated treatment of traditional Chinese medicine and western medicine for confirmed patients with coronavirus disease 2019 in Yangzhou city of Jiangsu province/ 江苏省扬州地区确诊新型冠状病毒肺炎患者的中西医结合临床诊治和效果评价
2020
Objective To summarize and evaluate the epidemiological characteristics, clinical symptoms, laboratory tests, treatment options and prognosis of novel coronavirus pneumonia (Coronavirus Disease 2019, COVID-19) in Yangzhou Methods The clinical data of 23 COVID-19 hospitalized patients in Yangzhou Infectious Disease Hospital were collected and analyzed Results Case characteristics: nucleic acid tests (oropharyngeal swabs) were positive in 23 patients, including1 severe case and 22 common cases, aged 23 to 72 years, with 10 males and 13 females There were 21 cases (91 3%) with contact history, among which familial clustering occured in 7 cases The average incubation period was 5 days ②Clinical symptoms mainly included cough, fever (78 3%), followed by sputum symptoms (26 1%), chest tightness and asthma (26 1% ), and digestive tract symptoms (8 7%) ③Hematological examination: the total number of white blood cells was normal, with low lymphocytes occurring in 16 patients, abnormal liver function in two patients at admission;triglycerides and cholesterol increased, and C reactive protein (CRP) decreased at discharge ④Imaging examinations: CT scan of the chest showed that multiple ground glass shadows was seen under the pleura, complicating with interstitial thickening ⑤Treatments: all the patients were treated by antiviral, anti-infective, and oxygen inhalation treatments Only one severe patient was given non-invasive ventilation All patients were discharged after negative results of the nucleic acid test Conclusions Positive nucleic acid test and multiple ground-glass shadows complicating with interstitial thickening by chest CT are important evidence for diagnosis of novel coronary pneumonia, and contact history of susceptible people, cough as well as fever symptoms, and low lymphocytes are important clinical manifestations of novel coronavirus pneumonia In clinic, comprehensive treatment of Chinese and western medicine is an effective treatment for COVID-19
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