Younger age as a bad prognostic factor in patients with carcinoma of the cervix.

Abstract Objective : To verify the influence of age on the prognosis of cervix carcinoma. Study design : Five hundred and sixty eight patients treated for a FIGO stage IB-IVA with radical irradiation in the Centre Hospitalier Universitaire Vaudois of Lausanne were subdivided according to the following age categories: ≤45, 46–60, 61–69 and >70 years. Taking the 46–60 years age group as the reference, the hazard ratios (HR) of death and corresponding 95% confidence intervals (95% CI) were estimated by means of a Cox multivariate analysis. Results : The 5-year survival rates were, respectively, 57%, 67%, 60% and 45%. For the youngest women the risk of death was significantly increased (HR = 2.00, 95% CI [1.32–3.00]) and was even more accentuated in advanced stages. Conclusion : Age under 45 years is a bad prognostic factor in carcinoma of the cervix.