The neurosteroid allopregnanolone protects retinal neurons by effects on autophagy and GABRs/GABAA receptors in rat glaucoma models

Makoto Ishikawa,Sanae Takaseki,Takeshi Yoshitomi,Douglas F. Covey,Charles F. Zorumski,Yukitoshi Izumi

The neurosteroid allopregnanolone protects retinal neurons by effects on autophagy and GABRs/GABAA receptors in rat glaucoma models

2020

Makoto Ishikawa
Sanae Takaseki
Takeshi Yoshitomi
Douglas F. Covey
Charles F. Zorumski
Yukitoshi Izumi

AbstractIn an ex vivo rat glaucoma model using dissected retinas, the neurosteroid allopregnanolone (AlloP) protects retinal ganglion cells (RGCs) via GABR/GABAA receptors. To determine the involve...

Keywords:

Ex vivo
Cell biology
Biology
Retinal ganglion
GABAA receptor
Retinal
Autophagy
Receptor
Allopregnanolone
Neuroactive steroid

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