MRI Contrast Media — Introduction and Basic Properties of the Blood Pool Agent Gadofosveset (Vasovist ® )

Twenty years ago, the first MRI contrast medium (MRI-CM) was introduced to the market: in 1988, Gd-DTPA (Magnevist®, Bayer Schering Pharma AG, Berlin, Germany) received market approval for clinical use in the United States, Europe and Japan. In the years to follow, application of MRI-CM became a widely established, powerful tool in MRI for improved diagnosis in approximately 30% of all MRI examinations worldwide [1, 2, 3, 4, 5].