Joint risks in a case-control study of esophageal cancer in Shanxi Province, People's Republic of China.

SU, W., HAN, X.Y., WANG, Y.P., WANG, Y.L., ZHN, Y.W., SASABA, T., HOSHIYAMA, Y. and TAGASHIRA, Y. Joint Risks in a Case-Control Study of Esophageal Cancer in Shanxi Province, People's Republic of China. Tohoku J. Exp. Med., 1994, 174 (2), 177-181 - A multifactorial analysis on the etiology of esophageal cancer was conducted based on a case-control study conducted in Shanxi. The study analyzed the data of 326 cases and 396 controls. The joint risks of two factors were calculated from dichotomous distributions. Three models of factor combinations were assessed: (1) two risk-enhancing factors, (2) two risk-reducing factors, and (3) a risk-enhancing and a risk-reducing factor. The observed joint risks were in the neighborhood of the multiplicative products of single acting risks of individual factors. This was a uniform pattern across three models.