A syndrome of polydactyly‐syndactyly and triphalangeal thumbs in three generations

A syndrome has been observed in four individuals in three generations in which there is polydactyly and syndactyly of the hands and feet and triphalangeal thumbs. The syndrome is characterized by an unusual malformation of the lower extremities, in which there is hypoplasia of the tibia and a large, curved fibula dislocated on the femur. The pattern of inheritance is consistent with the action of an autosomal dominant gene.