Sex as a predictive factor in metastatic colorectal cancer treated with bevacizumab containing chemotherapy.

e14128 Background: Recently, bevacizuamb induced hypertension was suggested as being a predictive factor for bevacizumab in metastatic colorectal cancer (mCRC) patients. However, there wasn’t any useful pretreatment predictive factor for bevacizumab in our clinic. So, in this study, we investigated the predictive factors for bevacizumab in mCRC. Methods: From 2002 to 2011, thirty mCRC patients received bevacizumab containing chemotherapy in Kyung HeeUniversity Hospital, Seoul. Among them, 27 patients had a measurable disease which adequate for response evaluation using Response Evaluation Criteria for Solid Tumors. We analyzed predictive factors for bevacizumabin these 27 patients using chi-squaretest and binary logistic regression analysis. Results: Median age was 57.0. Thirteen patients (48.1%) were male. ECOG performance status was 0,1,2 (29.6%/59.3%/11.1%). Eight patients had right side tumor and nineteen patients had left sided tumor. Fifteen patients had two metastatic sites. Sixteen patients receiv...