Anti-leukemia efficacy and mechanisms of action of SL-101, a novel anti-CD123 antibody-conjugate in acute myeloid leukemia

a novel anti-CD123 antibody-conjugate in acute myeloid leukemia Lina Han1*, Eric Rowinsky2, Chris Brooks2, Tomasz Zal3*, M. Anna Zal3*, Jared K Burks1, Jin Zhou4, Stefan Octavian Ciurea5, Gheath Alatrash5, Jorge Cortes1, Hagop M Kantarjian1, Michael Andreeff1, Farhad Ravandi1, and Marina Konopleva1 1Leukemia, 3Immunology, and 5Stem Cell Transplantation, MD Anderson Cancer Center, Houston, TX; 2Stemline Therapeutics, Inc,. New York, NY; 4Hematology, The First Affiliated Hospital of Harbin Medical University, Harbin, China