Expression of SFRP4 and DKK1 in cervical squamous cell carcinoma and the clinicopathological implications

Abstract To investigate the expression of SFRP4 and DKK1 in cervical squamous cell carcinoma and explore the clinicopathological implications. Immunohistochemistry and reverse transcriptase-polymerase chain reaction (RT-PCR) were used to detect the expressions of SFRP4 and DKK1 in 66 cervical squamous cell carcinoma and 26 normal cervical specimens. SFRP4 expression was significantly higher (P