Inhibitory Effect of the New Orally Active CCR4 Antagonist K327 on CCR4+CD4+ T Cell Migration into the Lung of Mice with Ovalbumin-Induced Lung Allergic Inflammation

Takashi Sato,Masato Komai,Miho Iwase,Katsuya Kobayashi,Harunobu Tahara,Etsuo Ohshima,Hitoshi Arai,Ichiro Miki

Inhibitory Effect of the New Orally Active CCR4 Antagonist K327 on CCR4+CD4+ T Cell Migration into the Lung of Mice with Ovalbumin-Induced Lung Allergic Inflammation

2009

Takashi Sato
Masato Komai
Miho Iwase
Katsuya Kobayashi
Harunobu Tahara
Etsuo Ohshima
Hitoshi Arai
Ichiro Miki

CC chemokine receptor 4 (CCR4) is expressed on Th2 cells, found in inflamed tissues of allergic diseases, and is therefore suspected to be involved in the pathogenesis of allergic diseases by controll

Keywords:

CCL23
Chemokine receptor CCR5
CCL5
CCL17
Immunology
CCL27
CC chemokine receptors
CCL13
Allergic inflammation
Chemistry

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