Conjugate Addition–Cyclization of a Cyanocuprate: 2‐Carbomethoxy‐3‐Vinylcyclopentanone

Conjugate addition–cyclization of a cyanocuprate: 2-carbomethoxy-3-vinylcyclopentanone intermediate: dimethyl (E)-2-hexenedioate product: 2-carbomethoxy-3-vinylcyclopentanone byproduct: Tetramethyltin Keywords: addition, to CC; annulation, carbocyclic-[5]; cyclization, condensation; metal-catalyzed reactions, palladium; assay methods, of diastereomeric purity by nmr analysis; lithium divinylcyanocuprate; copper cyanide, poison; copper cyanide, disposal; methyllithium, ethereal solution of; organotin compounds, disposal; organotin compounds, poison; tin alkyls, disposal; tin alkyls, poison