Correlation between bladder outlet obstruction and bladder cancer

Objective To investigate the role of the bladder outlet obstruction in the bladder cancer incidence and recurrence.Methods From Jan.2001 to Jan.2008 in our hospital,fourty-one cases of benign prostatic hyperplasia patients,with bladder cancer,were selected from 581 cases of benign prostatic hyperplasia patients,39 of them were randomly divided into two groups:One group were treated by surgery of bipolar transurethral plasma kinetic of prostatectomy(TUPKP) and transurethral resection of bladder tumor(TURBT) at the same time (observe group:23 cases),and the other group were treated by surgery of TURBT(control group:16 cases).All the patients were followed up for 12 to 36 months.Recurrence rate and recurrence time,as well as the suprapubic bladder tumor surgery in patients with stenosis of the bladder neck was also observed.Preoperative International Prostate Symptom Score (IPSS),maximum flow rate (Qmax),residual urine (RUV) and postoperative IPSS,Qmax,and RUV were tested for the difference between the two groups using t test.The variability of relapse rate after one year between the two groups were analyzed by χ~2 test.All statistical analysis was performed in SPSS 11.5.Results Postoperative IPSS,Qmax,RUV were (13±8)points,(19.3±9.5)ml/s,(18.7±11.6)ml in observe group and (20±7)points,(11.5±8.2)ml/s,(42.9±13.7)ml in control group (P<0.05),and the recurrence rate in 1 year was 34.78%(8/23) and 68.75% (11/16) in the two groups (P<0.05).Conclusions There is close correlation between bladder cancer and bladder outlet obstruction.The patients of bladder cancer combined with bladder outlet obstruction should be discharged bladder outlet obstruction at the same time. Key words: Bladder Cancer; Bladder outlet obstruction