Abstract 13992: Cost-effectiveness of On-pump and Off-pump Stable Multivessel Coronary Artery Bypass Grafting - MASS III Trial 5-year Follow-up

Introduction: Long-term cost-effectiveness of on-pump and off-pump coronary artery bypass graft surgery (CABG) is under debate. Hypotheses: Off-pump CABG was introduced with the aim of minimizing the non-physiological effects of extracorporeal circulation. Thus contributing to increase the cost-effectiveness. Methods: Between 2001 and 2006, 308 patients were randomized to on-pump CABG (n=153) or off-pump CABG (n=155). The 2 groups were well matched for baseline characteristics. Costs of all cardiovascular events and hospitalizations, medical consultations, diagnostic tests and medications were adjusted to inflation rates from 2001 to 2016. Costs were standardized to 2016 dollars. Patient QoL was assessed using the Short Form 36. Health state utilities were assessed using the SF-6D questionnaire. Results: Off-pump CABG patients had more incomplete revascularization (52.9% vs 42.5%; p=0.052). QoL improved significantly, but similarly, in the on-pump and off-pump CABG, respectively, from baseline (0.781 vs 0...