Association of serum omentin concentration with anthropometric, physiological, and biochemical parameters in obese individuals

Abstract Objective Omentin is a secretory protein produced in visceral adipose tissue. The potential protective action of omentin in metabolic disorders is not yet fully understood. The study aimed to determine the association of omentin with anthropometric, physiological, and biochemical parameters in obese patients. Research Methods and Procedures Sixty obese individuals and forty normal-weight controls were enrolled into the study. Anthropometric measurements were taken, systolic (SBP) and diastolic blood pressure (DBP) was recorded. Serum fasting glucose, insulin, homeostatic model assessment of insulin resistance (HOMA-IR), lipid profile, and serum omentin concentration were determined. Results The concentration of omentin in obese participants was significantly lower (145.5±33.3 vs. 383.6±92.9; p Conclusions A concentration of omentin is associated with cardiometabolic risk-related factors in obesity. Fasting insulin, adipose tissue percentage, and waist circumference can be considered candidates for markers of omentin concentration in obese subjects.