The insulin-like growth factor-I receptor kinase inhibitor NVP-AEW541 induces apoptosis in acute myeloid leukemia cells exhibiting autocrine insulin-like growth factor-I secretion.

P L Tazzari,Giovanna Tabellini,Roberta Bortul,Veronica Papa,Camilla Evangelisti,Tiziana Grafone,Giovanni Martinelli,J A McCubrey,Am Martelli

The insulin-like growth factor-I receptor kinase inhibitor NVP-AEW541 induces apoptosis in acute myeloid leukemia cells exhibiting autocrine insulin-like growth factor-I secretion.

2007

P L Tazzari
Giovanna Tabellini
Roberta Bortul
Veronica Papa
Camilla Evangelisti
Tiziana Grafone
Giovanni Martinelli
J A McCubrey
Am Martelli

The insulin-like growth factor-I receptor kinase inhibitor NVP-AEW541 induces apoptosis in acute myeloid leukemia cells exhibiting autocrine insulin-like growth factor-I secretion

Keywords:

Autocrine signalling
Cancer research
Insulin-like growth factor
Growth factor
Programmed cell death
Cell growth
Myeloid leukemia
Kinase
Biology
Receptor

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