Diagnostic significance of chemiluminescent response of neutrophil granulocyte in children with lymphadenopathy

Chemiluminescent response of the blood neutrophilic granulocytes was evaluated during the diagnostic period in 22 patients with Hodgkin's disease, 35 with nonspecific lymphadenopathies, and 24 patients with tuberculous infection aged 7-14 years. Disorders in spontaneous and induced chemiluminescence of neutrophils were detected in all patients, and were the most pronounced and stable in patients with Hodgkin's disease. Evaluation of neutrophilic chemiluminescent response in these patient groups leads to a more accurate diagnosis of lymphadenopathies of different origin.