Влияние наночастиц аморфного высокодисперсного кремнезема на морфологическую структуру внутренних органов крыс

The comparative study on the effect of powders of amorphous highly disperse SiO 2 nanoparticles (6–7 nm and 54–55 nm) and the powder of the standard Lyuberets quartz PQ3 after single intratracheal administration in the dose of 50 mg in 3month experiment was conducted. Under the experiment following changes were observed: transitory decrease of the relative mass of adrenal glands as a sign of the stress effect; persistent hyperemia in inner organs (lungs, liver, kidneys, myocardium), infiltration of their stroma by histiocytes, leucocytes, lymphocytes and plasma cells and the focus of large granular protein dystrophy. The powders of nanoparticles caused more expressed damage in bronchi mucose and morphological disorders in kydney than the powder of the standard Lyuberets quartz PQ3. There was concluded, that inhalanion of amorphous highly disperse SiO 2 nanoparticles into worker’s organism in production conditions is dangerous to health.