Cyanogen Chloride. Part 1. Preparation. Part 2. Toxicity: Median Lethal Concentration for Mice

Abstract : Object: One of the objects of project A 3.3-1 is to reinvestigate the toxicity of cyanogen chloride under the latest conditions for conducting animal experimentation and establish the minimum lethal concentration for 2 minutes, for 10 minutes, and for 30 minutes. The object of the work described in this report was to synthesize pure cyanogen chloride, to study the literature pertaining to its wartime use and to its stability and chemical constitution, to determine its median lethal concentration for white mice exposed for 2 minutes, 10 minutes, and 30 minutes and observed for 10 days, and to compare the value of cyanogen chloride as a war gas with phosgene and hydrocyanic acid.