The identification of 6‐methoxy 8‐aminoquionoline as a metabolite of primaquine in man
1975
The identification of 6-methoxy 8-aminoquinoline as a metabolite of Primaquine, an important antimalarial drug, is described. The metabolite is present in urine, plasma and erythrocytes following drug ingestion. It was identified by mass fragmentography of its 1H and 2H acetate and the acetate produced from authentic material. No evidence of further metabolites was obtained.
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