2050-P: A Multifactorial Telemedical Care Model for Long-Term Treatment of Obesity—A Randomized Controlled Trial

Lifestyle interventions are indicated as first-line therapy to fight obesity focusing on various aspects of a healthy lifestyle. However, as most of these lifestyle programs only include single components, we designed a multifactorial, telemedical and group-based seminar program to improve weight loss in overweight individuals. Overweight volunteers (BMI ≥25 kg/m 2 ) were randomized into a starting intervention group (SI, n=15) or a waiting list control group (WL, n=15). The multicomponent intervention consisted of a (1) group-based seminar program addressing low-carbohydrate nutrition, physical activity, and the carbohydrate-blood glucose-insulin relationship. Further components used were (2) low-carbohydrate formula diet, (3) flash-glucose-monitoring devices and (4) telemedical supervision. Both groups received telemedical devices at baseline. After the 12-weeks intervention phase of SI, WL started with the same intervention. Participants received monthly calls by coaches until week 26. Data were recorded before and after 12, 26 and 52 weeks of follow-up. After 12 weeks of intervention, SI demonstrated a stronger reduction in weight compared to WL (-7.8 kg vs. -1.5 kg; P A multifactorial program leads to long-term clinically relevant weight reductions and improvements in cardiovascular risk factors in overweight individuals. Disclosure M. Rohling: None. K. Martin: None. S. Ellinger: None. S. Martin: Consultant; Self; Almased Wellness GmbH, AstraZeneca, Lilly Diabetes. K. Kempf: Speaker9s Bureau; Self; cognomed, Kirchheim Verlag.