Transcription factor E2F3a regulates CASP8AP2 transcription and enhances sensitivity to chemotherapeutic drugs in acute lymphoblastic leukemia

Fei-Fei Liu,Kai-Ling Wang,Li-Ping Deng,Xiao Liu,Minyuan Wu,Wang T,Lei Cui,Zhigang Li

Transcription factor E2F3a regulates CASP8AP2 transcription and enhances sensitivity to chemotherapeutic drugs in acute lymphoblastic leukemia

2018

Fei-Fei Liu
Kai-Ling Wang
Li-Ping Deng
Xiao Liu
Minyuan Wu
Wang T
Lei Cui
Zhigang Li

Background Low expression of E2F3a and caspase 8 associated protein 2 (CASP8AP2) are associated with poor prognosis of childhood acute lymphoblastic leukemia (ALL).

Keywords:

Cancer research
Caspase 8 associated protein 2
Transcription factor
Immunology
Transcription (biology)
Transcriptional regulation
Lymphoblastic Leukemia
Medicine
Childhood Acute Lymphoblastic Leukemia
Reporter gene
Daunorubicin
Cell cycle
Cell growth
Wild type
Chromatin immunoprecipitation
Promoter

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