Dammarane saponins from Panax ginseng

Abstract From the dried roots of Panax ginseng two new minor dammarane saponins named koryoginsenoside-R 1 and -R 2 were isolated, along with fourteen known saponins. On the basis of spectral and chemical evidence, the structures of the new saponins were elucidated as 6-O-[ trans butenoyl-(1 → 6)-β- d -glucopyranosyl ]-20-O-β- d -glucopyranosyl dammar-24-en-3β,6α,12β,20( S )-tetrol and 3-O-[β- d -glucopyranosyl-(1 → 2)-β- d -glucopyranosyl ]-20-O-[β- d -glucopyranosyl-(1 → 6)-β- d -glucopyranosyl ] dammar-22-en-3β,12β,20( S ),-25-tetrol, respectively.