Myocarditis in Multisystem Inflammatory Syndrome in Children (MIS-C) Associated with Coronavirus Disease 2019 (COVID-19).

Cardiac involvement as a complication of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) infection in children is a relatively new entity. We present our initial experience managing children with COVID-19-related acute myocardial injury. The 3 patients presented here represent a spectrum of the cardiac involvement noted in children with COVID-19-related Multisystem Inflammatory Syndrome in Children (MIS-C), including myocarditis presenting as cardiogenic shock or heart failure with biventricular dysfunction, valvulitis, coronary artery changes and pericardial effusion.