Gene Polymorphisms in Periodontitis in a Taiwan Population

Multifactorial diseases such as human periodontitis often involve complex interactions among multiple genes and environmental factors. Reports of genetic susceptibility to periodontitis are increasing. This study reviewed the literature (including unpublished data) on putative genetic risk factors for susceptibility to aggressive and chronic periodontitis in Taiwan, where 98% of the population is Han Chinese. The role of genetic single nucleotide polymorphisms in susceptibility to periodontitis was also investigated. (J Taiwan Periodontol, 21(1):23-50, 2016)