Simethicone solid self-emulsifying preparation and preparation process thereof
2016
The invention discloses a simethicone solid self-emulsifying preparation. The preparation is prepared from, by weight, 2.0-6.0% of simethicone, 2.0-30.0% of emulsifier, 1.0-20.0% of auxiliary emulsifier, 50.0-90.0% of pharmaceutically-acceptable solid adsorption material and 0-10.0% of wetting agent. The invention further provides a preparation method of the simethicone solid self-emulsifying preparation. The method is easy and convenient to operate, low in cost and suitable for industrial production; the obtained product has the advantages of being good in taste, uniform in distribution, high in solubility, stable in quality and the like; the preparation is rapid in dissolution, easy to take, rapid in effect and suitable for the aged, children and people who have difficulty in swallowing, the compliance of patients is increased, and the preparation has more advantages on the aspects of packaging, carrying, transporting and the like compared with a traditional liquid simethicone suspension and emulsifier and has good application prospects on the aspects of treating symptoms such as abdominal distension, abdominal discomfort, dyspepsia and postoperative abdominal distension caused when gas gathers in the abdomen.
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