Detection of Human Papillomavirus DNA from Epithelial Lessions of Vulvar Dystrophies by lsotope-labelled DNA Probes

Vulvar biopsy specimens from nine patients with vulvar dystrophy were examined for the presence of human papillomavirus DNA by Southern blot hybridization. The results showed that two of eight hypcrplastic dystrophies contained HPV 16 homologous sequence, one contained HPV 33 homologous sequence and three cases were positive for HPV relative sequence HPV relative sequence was also detected in one case with mixed dystrophy. So total proportion of HPV in the nine vulvar specimens was seventy seven percent, Th...