Hippocampal LTP observed by Multi-Array-Electrodes

Hippocampal LTP, well known as the learning model, is induced by tetanic stimulation to CA1 region in the hippocampus. The microelectrode techniques is advantageous in temporal resolution, while that of optical probing by functional dyes has advantage to spatial resolution. For long period observation from wider area, the recording by multi-array-electrode (MAE) is desirable. We applied MAE to the hippocampal slice to analyze the signal transudation property at the cellular level.