Study on the correlation between lymphovascular invasion and lymph node ratio in patients withbreast cancer

Objective To investigate the relationship between lymphovascular invasion (LVI) and lymph node ratio (LNR) in breast cancer. Methods The positive rate of LVI in one hundred and eighteen breast cancer patients was detected by immunohistochemical staining with monoclonal antibody D2-40 grade CK pan immunohistochemical staining to analyze the relationship between LVI and LNR. Results The positive rate of LVI was 37.3% (42/118), significantly related to lymph node ration, the number of lymphatic metastasis and histological grade ( χ2=9.186, 6.996, 18.340, P=0.010, 0.030, 0.000). Conclusion Lymphovascular invasion can be used as an important reference index for the diagnosis of axillary lymph node metastasis of breast cancer, and the higher the lymph node ratio, the higher the incidence of lymphatic invasion. Key words: Breast neoplasms; Lymphatic vessels; Lymphatic metastasis; Lymph node ratio; Keratinocytes