닭의 추백리 감염 후 간장 내의 단백체 변화 연구

Salmonella pullorum in poultry is a signficant health problem which causes substantial economic loss. This study was conducted to characterize and identify protein expression profiles of chicken liver after S. pullorum challenge. To identify the differentially expressed chicken liver proteins after S. pullorum, we have used two-dimensional electrophoresis with MALDI-TOF mass spectrometry. Total 14 protein spots were selected from two-dimensional electrophoresis. 8 proteins were up-regulated and 6 proteins were down-regulated at the chicken liver infected S. pullorum. In conclusion, this study could be used to the determine characterize and identify protein expression profiles of chicken liver infected S. pullorum.