A New Class of Dengue and West Nile Virus Protease Inhibitors With Submicromolar Activity in Reporter Gene DENV-2 Protease and Viral Replication Assays.

Nikos Kühl,Dominik Graf,Josephine Bock,Mira A. M. Behnam,Mila M. Leuthold,Christian D. Klein

A New Class of Dengue and West Nile Virus Protease Inhibitors With Submicromolar Activity in Reporter Gene DENV-2 Protease and Viral Replication Assays.

2020

Nikos Kühl
Dominik Graf
Josephine Bock
Mira A. M. Behnam
Mila M. Leuthold
Christian D. Klein

Dengue and West Nile virus are rapidly spreading global pathogens for which no specific therapeutic treatments are available. One of the promising targets for drug discovery against dengue and othe...

Keywords:

West Nile virus
Protease
Virology
Biochemistry
Chemistry
Dengue fever
Drug discovery
Viral replication
Reporter gene

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