Minimálisan invazív, endoszkóppal asszisztált, transcribriform reszekció a koponyaalap rosszindulatú daganatainak sebészetében = Minimally invasive endoscopic transcribriform resection of malignant lesions of the skull base
2019
Absztrakt: Bevezetes: A koponyaalapot is erintő rosszindulatu sinonasalis
daganatok legtobb tipusa sebeszi ellatast tesz szuksegesse. Az esetek nagy
reszeben ma mar lehetőseg nyilik minimalisan invaziv, craniofacialis kulső
feltaras nelkuli, endoszkopos műtetet vegezni. Celkitűzes:
Kozlemenyunkben a koponyaalapot destrualo rosszindulatu daganatok sebeszi
megoldasa celjabol alkalmazott endoszkopos transcribriform feltarassal szerzett
tapasztalatainkrol szamolunk be. Modszer: 2015. februar es
2017. julius kozott negy ferfi es 1 nőbetegen hajtottunk vegre műtetet. Az
atlageletkor 64,6 ev volt (59–70, median: 66). Minden műtet az orruregen
keresztul, minimalisan invaziv behatolassal, endoszkopos vizualizacio mellett
tortent, a koponyaalap transcribriform feltarasaval es reszekciojaval. A műtet
indikaciojat 2 esetben Kadish szerinti C-stadiumu esthesioneuroblastoma, 1
esetben T3N0 sinonasalis nem differencialt carcinoma, 1 esetben T1N0
intestinalis tipusu adenocarcinoma, illetve tovabbi 1 esetben
T4N0-laphamcarcinoma kepezte. Eredmenyek: A betegek kovetesi
ideje 14 es 46 honap kozott alakult, atlagosan 22,8 honap volt. A műtetek soran
intraoperativ szovődmeny nem lepett fel. A posztoperativ időszakban egy beteg
eseteben liquorrhoea, illetve emellett pneumocephalus alakult ki, melyek
lumbalis drenazs alkalmazasa es konzervativ kezeles mellett rendeződtek. Az
utankovetes soran egyik beteg eseteben sem eszleltunk recidivat.
Kovetkeztetes: Az elulső koponyaalap rosszindulatu
daganatainak sebeszi megoldasakent az endoszkopos, transnasalis, transcribriform
feltarassal vegzett reszekcio kivalo alternativaja a kulső feltarasbol vegzett
műteteknek a biztonsagos kivitelezhetőseg es a megfelelő onkologiai eredmeny
eleresenek szempontjabol is. Orv Hetil. 2019; 160(40): 1584–1590.
| Abstract: Introduction: Malignant tumours of the sinonasal region –
including those with invasion of the skull base – necessitate surgical
resection. The majority of the cases give an opportunity to perform the
procedure via minimally invasive, endoscopic approach, without
external, craniofacial surgery. Aim: To assess our clinical
experience in treating anterior skull base malignancies, performing minimally
invasive endoscopic transcribriform resection. Method: Between
February 2015 and July 2017, four male and one female patient underwent
minimally invasive, endoscopic skull base procedure. The mean age was 64.6 years
(59–70, median: 66). Every surgery was performed via
transnasal, endoscopic transcribriform approach. In two cases Kadish C
esthesioneuroblastomas, while in one case a T3N0 sinonasal non-differentiated
carcinoma, a T1N0 intestinal type adenocarcinoma and a T4N0 squamous cell
carcinoma was the indication of surgery, respectively. Results:
The mean follow-up time was 22.8 months, between 14 and 46 months.
Intraoperative complications did not occur during the procedures. Regarding the
postoperative period, liquorrhoea and pneumocephalus occurred in one case.
Complications were solved with lumbar drainage. During follow-up, neither
residual nor recurrent tumour was observed in our patients.
Conclusion: Endoscopic transcribriform resection of the
skull base malignancies is a safe and viable alternative to the traditional open
approach. Orv Hetil. 2019; 160(40): 1584–1590.
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