Concordance of Genomic Variants in Matched Primary Breast Cancer, Metastatic Tumor, and Circulating Tumor DNA: The MIRROR Study

Fernando Ángel Moreno,Javier Gayarre,Sara López-Tarruella,María del Monte-Millán,Antonio C. Picornell,Enrique Alvarez,José Ángel García-Sáenz,Yolanda Jerez,I. Márquez Rodas,Isabel Echavarria,Maribel Palomero,C Bueno,Ana María Aragón Bodí,Marta Muñoz,Ricardo González del Val,Oscar Bueno,María Cebollero-Presmanes,Inmaculada Ocaña,Ainhoa Arias,Paula Romero,T. Massarrah,R. Ramos Medina,Miguel Martin

Concordance of Genomic Variants in Matched Primary Breast Cancer, Metastatic Tumor, and Circulating Tumor DNA: The MIRROR Study

2019

PURPOSEGenetic heterogeneity between primary tumors and their metastatic lesions has been documented in several breast cancer studies. However, the selection of therapy for patients with metastatic...

Keywords:

primary breast cancer
Breast cancer
Circulating tumor DNA
metastatic tumor
Concordance
metastatic lesions
Cancer research
Medicine

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