Stromal aminopeptidase N expression: correlation with angiogenesis in non-small-cell lung cancer
2009
Purpose
Aminopeptidase-N (APN) is a membranebound protein that acts as a zinc-binding protease and participates in extracellular proteolysis. APN plays important roles in tumor progression through promoting invasion and metastasis, prolonging survival of tumor cells, and tumor angiogenesis.
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