Immunomodulatory activity of Withania somnifera (L.)

The present study was undertaken to evaluate the ef fect of some selected medicinal plants on immunomod ulatory activity that comprises of screening to identify th e activity of ethanolic extract of medicinal plants on humoral and cell mediated immunity (specific immune response). Experiments were conducted in vivo in Swiss albino mice. Withania somnifera (WS) ethanolic extract was found to enhance humoral immune response on 7 th day by 12 % as compared to the standard control cyclophosphamide t hat exhibited 54% humoral immune response, where as cell mediated immune response was observed with an enhan cement in the values (19.27%) in comparison with co ntrol cyclosporine (37.63%).