Effects of stomach inflation on haemodynamic and pulmonary function during spontaneous circulation in pigs

Abstract Aim Stomach inflation during mask ventilation is frequent, but the effects on haemodynamic and pulmonary function are unclear. We evaluated the effects of stomach inflation on haemodynamic and pulmonary function during spontaneous circulation in a porcine model. Methods Randomised prospective animal study. After randomisation, in 23 domestic pigs the stomach was inflated every 90 s with 0 L (control; n  = 8), 0.5 L ( n  = 7) or 1 L ( n  = 8) ambient air. Results After 22.5 min, i.e. 8.5 L in the 0.5 L and 17 L in the 1 L stomach inflation group, stomach inflation increased central venous pressure (median) (control: 10 mmHg vs. 1 L: 23 mmHg, P P P P 2 O vs. 0.5 L: 8 mL/cmH 2 O, P 2 O, P 2 O vs. 0.5 L: 69 cmH 2 O, P 2 O, P P P 2 /min vs. 1 L: 19 mL O 2 /min, P P Conclusions Stomach inflation with 1 L when compared to 0.5 L increments resulted in faster haemodynamic and pulmonary failure and increased mortality. Stomach inflation may cause a hyper-acute abdominal compartment syndrome.