Prognostic factors in the progression of intervertebral disc degeneration: which patient should be targeted with regenerative therapies?

Objective Possible regenerative treatments for lumbar intervertebral disc degeneration (DD) are rapidly emerging. There is consensus that the patient that would benefit most has early‐stage DD, with a predicted deterioration in the near future. To identify this patient, the aim of this study was to identify prognostic factors for progression of DD.