Questionable suitability of OECD 237 protocol in risk assessment scheme
2018
Persistent xenobiotics are potentially hazardous for the bee larvae despite that they are not directly exposed in
contrary to adult foraging bees. The crucial phase of larval development is the first six days after hatching
when young larva grows exponentially and during this phase larvae are potentially exposed to xenobiotics via
diet. That is why the life cycle of honeybee is still a great challenge for scientists. OECD reflected “this need”
and adopted the OECD 237 protocol (Honey bee (Apis mellifera) larval toxicity test, single exposure) on 26th
July 2013. The protocol addresses the requirements formulated by the United States, Canada, and Europe to
test the toxicity of chemicals compounds on larvae fed with spiked food under laboratory conditions in a tier1
strategy.
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