Heterogeneity of Adult Polycystic Kidney Disease Analysis of an APKD Family Unlinked to 3’HVR

The majority of adult polycystic kidney disease (APKD) cases belong to the autosomal dominant category, occurring with a gene frequency of 1:1000 in Europe and North America. Although reliable statistical data are still lacking, APKD is not rare in China. In 1985, Reeders reported that PKD1, the APKD gene, was located on the short arm