THE EFFECT OF IRRADIATION COMBINED WITH BLOOD LOSS ON THE COURSE AND THE OUTCOME OF PREGNANCY IN EXPERIMENTAL ANIMALS

White female rats were subjected to a total single x-ray irradiation of (300r). Immediately after the irradiation blood letting (15 to 30% of the total blood volume) was carried out. 2 series of experiments were conducted on pregnant and non-gravid animals. The total of 155 rats and 882 offsprings were examined. It was established that the course of radiation sickness in pregnant animals differs from that of non-gravid ones (notably regeneration of the red blood in pregnant rats begins earlier than in non-gravid). Blood loss of average degree directly after the irradiation intensifies the regenerative function of the bone marrow in the maternal body and decreases the degree of affection of the hemopoietic organs of the fetus. Extensive blood loss combined with irradiation increases the percentage of stillbirths, although the regeneraiive function of the bone marrow in the maternal boody, is intensified. (tr-auth)