In vivo study of erysolin metabolic profile by ultra high performance liquid chromatography coupleded to Fourier transform ion cyclotron resonance mass spectrometry

Binglong Li,Hui Zhou,Guochun Yang,Fei Han,Yanting Li,Yongfeng Gao,Jinwei Gao,Feng Zhang,Lixin Sun

In vivo study of erysolin metabolic profile by ultra high performance liquid chromatography coupleded to Fourier transform ion cyclotron resonance mass spectrometry

2018

Binglong Li
Hui Zhou
Guochun Yang
Fei Han
Yanting Li
Yongfeng Gao
Jinwei Gao
Feng Zhang
Lixin Sun

• This study systematically investigated the metabolic profile of erysolin in rats using the approach of UHPLC-FT-ICR-MS, and the metabolic profile of erysolin in vivo was revealed preliminarily for the first time.

Keywords:

Analytical chemistry
High-performance liquid chromatography
Chemistry
Nuclear magnetic resonance
Fourier transform ion cyclotron resonance
Chromatography
Mercapturic acid
Metabolic pathway
Elution
Conjugate
Mass spectrometry
Glutathione
In vivo

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