Development, characterization and evaluation of mucoadhesive microspheres of amoxicillin trihydrate

Mucoadhesive microspheres include microparticles and microcapsules (having a core of the drug) of 1 -1000µm in diameter and consisting either entirely of a mucoadhesive polymer o r having an outer coating of it, respectively. Amo xicillin microspheres were formulated by using solvent evaporation technique. Using Eudragit RS 100 as matrix poly mer. Evaluation of the Prepared Mucoadhesive Microspheres done for % yield, Particle size analysis, Particle size d istribution Angle of repose, Determination of drug content, Shape and surface characterizat ion, drug entrapment and finally cu mulat ive drug release fro m microspheres.