Antioxidant bioaccessibility from wheat aleurone throughout the canine gastrointestinal tract: an in vitro study (1044.14)

Enhancing overall health status through nutrition has growing interest in humans and animals and thus, the market for food and feed formulations with added functional dietary ingredients is on the rise. Health-promoting properties of wheat are documented in vivo and in vitro, and are partially attributed to antioxidant compounds in the bran fraction. Cargill isolates the aleurone fraction from wheat bran which is used as an ingredient in companion animal diets with the expectation of promoting a healthier diet. However, for bioactive compounds to be efficacious, they must be bioaccessible (available for absorption) during the digestive process. Our studies indicated antioxidants from aleurone are more bioaccessible than those from beet pulp fiber (BP) in an in vitro dynamic digestive system (TNO) validated for the GI-tract of dogs. Results show low molecular weight antioxidant compounds become bioaccessible in the jejunum compartment of the small intestine but not in the ileum (TIMdog-1), and antioxidant ...