Osteopontin: a novel inflammatory mediator of cardiovascular disease.

1. Abstract2. Introduction3. Osteopontin Structure and Cell Binding4. Role in Vascular Disease4.1. Role in angiogenesis4.2. Role in inflammation4.3. Role in calcification4.4. Aneurysms/dissections5. Role in Heart Disease5.1. Osteopontin and valvular pathology5.2. Osteopontin and heart failure5.3. Role of osteopontin in myocardial infarction5.4. Possible mechanisms mediating action in the heart6. Clinical Relevance/Significance7. Conclusions8. Acknowledgements9. References