A case of luteinized thecoma associated with sclerosing peritonitis treated with GnRH agonist and tamoxifen

Luteinized thecoma associated with sclerosing peritonitis is a rare and enigmatic condition for which there is no standard treatment strategy. We report a case of luteinized thecoma associated with sclerosing peritonitis in a 31-year-old woman with a history of bipolar disorder. The patient presented with abdominal distension, and imaging examinations revealed bilateral ovarian tumors with ascites and pleural effusion. A diagnostic laparotomy was performed and showed bilateral ovarian tumors with polypoid surface contours, yellow watery ascites, and diffusely indurated omentum. Left salpingo-oophorectomy followed by right salpingo-oophorectomy and omentectomy were performed. Twenty-one days after surgery, the patient developed an intestinal obstruction resistant to conservative treatment. Gonadotropin-releasing hormone agonist and tamoxifen were administered to gradually improve the obstructive symptoms. After 18 months of follow-up, she is asymptomatic. Luteinized thecoma associated with sclerosing peritonitis may be a non-neoplastic condition that responds well to medical therapy.