Síndromes paraneoplásicas: o que o cirurgião-dentista precisa saber?: [revisão]

Introducao: o termo paraneoplasia e um conjunto de disturbios clinicos, bioquimicos, hormonais, neurologicos e/ou hematologicos associados com neoplasias malignas, mas nao diretamente relacionados com invasao tumoral primaria ou metastase. As sindromes paraneoplasicas podem ser o primeiro sinal de uma malignidade. Revisao de literatura: as sindromes que estao mais comumente relacionadas com a pratica odontologica sao: de Lambertt-Eaton, de Gardner, de Cowden, de Peutz-Jeghers, de Sjogren, a neoplasia endocrina multipla, a neurofibromatose multipla de Von Recklinghausen, o carcinoma nevoide de celulas basais, a acantose nigrans e o penfigo paraneoplasico. Conclusao: o diagnostico precoce das neoplasias malignas favorece o seu prognostico e as sindromes paraneoplasicas auxiliam neste diagnostico. E de suma importância que os Cirurgioes-dentistas conhecam tais sindromes de modo a diagnostica-las o mais rapido possivel e encaminhar os pacientes ao tratamento especializado. Introduction: the term paraneoplastic is a clinical, biochemical, hormonal, neurological and/or associated disorder with hematologic malignancies, but not directly related to primary tumor invasion and metastasis. Paraneoplatic syndromes may be the first sign of a malignancy. Review of literature: the syndromes that are most commonly related to dentistry are of lambertt-Eaton, Gardner, Cowden disease, Peutz-Jeghers, Sjogren, multiple endocrine neoplasic, multiple neurofibromatosis of Von Recklinghausen, nevoid basal cell carcinoma, acanthosis nigrans and pemphigus paraneoplastic. Conclusion: early diagnosis of malignant neoplasms favors prognosis and paraneoplastic syndromes assist in diagnosis. It is important that surgeons-dentists know these events in order to diagnose them as soon as possible and refer these patients to specialized treatment.