ADAMTS9 is Silenced by Epigenetic Disruption in Colorectal Cancer and Inhibits Cell Growth and Metastasis by Regulating Akt/p53 Signaling

Ling Chen,Jun Tang,Yixiao Feng,Shuman Li,Qin Xiang,Xiaoqian He,Guosheng Ren,Weiyan Peng,Tingxiu Xiang

ADAMTS9 is Silenced by Epigenetic Disruption in Colorectal Cancer and Inhibits Cell Growth and Metastasis by Regulating Akt/p53 Signaling

2017

Ling Chen
Jun Tang
Yixiao Feng
Shuman Li
Qin Xiang
Xiaoqian He
Guosheng Ren
Weiyan Peng
Tingxiu Xiang

Background/Aims: ADAMTS (disintegrin-like and metalloproteinase with thrombospondin motifs) proteins are extracellular zinc metalloproteinases that play an import

Keywords:

Protein kinase B
Thrombospondin
Colorectal cancer
Matrix metalloproteinase
Extracellular
Epigenetics
Biology
Cancer research
ADAMTS
Metastasis
Angiogenesis
Extracellular matrix assembly
Cell cycle
Tumor suppressor gene
Cell growth

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